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研究業績

論文

2016年
  1. Tabe Y, Hatanaka Y, Nakashiro M, Sekihara K, Yamamoto S, Matsushita H, Kazuno S, Fujimura T, Ikegami T, Nakanaga K, Matsumoto H, Ueno T, Aoki J, Yokomizo T, Konopleva M, Andreeff M, Miida T, Iwabuchi K, Sasai K. Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells.INTERNATIONAL JOURNAL OF RADIATION BIOLOGY;92(1):24-34.2016
  2. Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Ma W, Lee HC, Orlowski R, Sarbassov dos D, Lorenzi PL, Huang X, Neelapu SS, McDonnell T, Miranda RN, Wang M, Kantarjian H, Konopleva M, Davis RE, Andreeff M. ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.Science Signaling,9(415):ra17,2016
  3. Tsuyoshi Saito, Keisuke Akaike, Aiko Kurisaki-Arakawa, Midori Toda-Ishii, Kenta Mukaihara, Yoshiyuki Suehara, Tatsuya Takagi, Kazuo Kaneko, Takashi Yao TERT promoter mutations are rare in bone and soft tissue sarcomas of Japanese patients.Molecular and Clinical Oncology,4(1),61-64,2016
2015年
  1. Harada M, Benito J, Yamamoto S, Kaur S, Arslan D, Ramirez S, Jacamo R, Platanias L, Matsushita H, Fujimura T, Kazuno S, Kojima K, Tabe Y, Konopleva M. The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression.Oncotarget,6(35),37930-47,2015
  2. Yoko Tabe,Kensuke Kojima ,Shinichi Yamamoto, Kazumasa Sekihara,Hiromichi Matsushita,Richard Eric Davis, Zhiqiang Wang, Wencai Ma,Jo Ishizawa,Saiko Kazuno,Michael Kauffman, Sharon Shacham,Tsutomu Fujimura,Takashi Ueno,Takashi Miida,Michael. Ribosomal biogenesis and translational flux inhibition by the selective inhibitor of nuclear export (SINE) XPO1 antagonist KPT-185.PLOS ONE, 10(9),e0137210,2015
  3. Shukuya T, Yamanaka T, Seto T, Daga H, Goto K, Saka H, Sugawara S, Takahashi T, Yokota S, Kaneda H, Kawaguchi T, Nagase S, Oguri T, Iwamoto Y, Nishimura T, Hattori Y, Nakagawa K, Nakanishi Y, Yamamoto N. Nedaplatin plus docetaxel versus cisplatin plus docetaxel for advanced or relapsed squamous cell carcinoma of the lung (WJOG5208L): a randomised, open-label, phase 3 trial.LANCET ONCOLOGY,16(16),1630-1638,2015,DOI:10.1016/S1470-2045(15)00305-8
  4. Munakata S, Tashiro Y, Nishida C, Sato A, Komiyama H, Shimazu H, Dhahri D, Salama Y, Eiamboonsert S, Takeda K, Yagita H, Tsuda Y, Okada Y, Nakauchi H, Sakamoto K, Heissig B, Hattori K. Inhibition of Plasmin Protects Against Colitis in Mice by Suppressing Matrix Metalloproteinase 9-mediated Cytokine Release From Myeloid Cells. Gastroenterology,148（3）,565-578,2015
  5. Ishizawa J, Kojima K, Hail N Jr, Tabe Y, Andreeff M. Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein. Pharmacology & Therapeutics,153:25-35,2015
  6. Shirane S, Araki M, Morishita S, Edahiro Y, Takei H, Yoo Y, Choi M, Sunami Y, Hironaka Y, Noguchi M, Koike M, Noda N, Ohsaka A, Komatsu N JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms. Haematologica,100（2）,e46-48,2015
  7. Yagishita S, Fujita Y, Kitazono S, Ko R, Nakadate Y, Sawada T, Kitamura Y, Shimoyama T, Maeda Y, TakahashiF, Takahashi K, Tamura T, Koizumi F. Chemotherapy-Regulated microRNA-125-HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small cell lung cancer.MOLECULAR CANCER THERAPEUTICS,14(6),1414-23,2015
  8. Fukasawa K, Kagaya S, Maruyama S, Kuroiwa S, Masuda K, Kameyama Y, Satoh Y, Akatsu Y, Tomura A, Nishikawa K, Horie S, Ichikawa Y A novel compound, NK150460, exhibits selective antitumor activity against breast cancer cell lines through activation of aryl hydrocarbon receptor. MOLECULAR CANCER THERAPEUTICS,14（2）,343-54,2015
  9. Watanabe G, Ishida T, Furuta A, Takahashi S, Watanabe M, Nakata H, Kato S, Ishioka C, Ohuchi N. Combined Immunohistochemistry of PLK1, p21, and p53 for Predicting TP53 Status: An Independent Prognostic Factor of Breast Cancer.AMERICAN JOURNAL OF SURGICAL PATHOLOGY,39(8),1026-34,2015
  10. Harada-Shirado K, Ikeda K, Ogawa K, Ohkawara H, Kimura H, Kai T, Noji H, Morishita S, Komatsu N, Takeishi Y Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms. British journal of haematology,168(3),338-349,2015
  11. Sugano K, Okuyama T, Iida S, Komatsu H, Ishida T, Kusumoto S, Uchida M, Nakaguchi T, Kubota Y, Ito Y, Takahashi K, Akechi T. Medical Decision-Making Incapacity among Newly Diagnosed Older Patients with Hematological Malignancy Receiving First Line Chemotherapy: A Cross-Sectional Study of Patients and Physicians.PLoS One.,10(8),e0136163,2015
  12. Morishita S, Takahashi K, Araki M, Hironaka Y, Sunami Y, Edahiro Y, Tsutsui M, Ohsaka A, Tsuneda S, Komatsu N Melting Curve Analysis after T Allele Enrichment (MelcaTle) as a Highly Sensitive and Reliable Method for Detecting the JAK2V617F Mutation. PloS one.,10（3）,e0122003,2015
  13. Tatsuya Takagi, Hirohisa Katagiri, Yongji Kim, Yoshiyuki Suehara, Daisuke Kubota, Keisuke Akaike, Midori Ishii, Kenta Mukaihara, Taketo Okubo, Hideki Murata, Mitsuru Takahashi, Kazuo Kaneko, Tsuyoshi Saito Skeletal metastasis of unknown primary origin at the initial visit: a retrospective analysis of 286 cases.PLoS One,10(6),e0129428,2015
  14. Ito Y, Kawano H, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Arai H, Kobayashi T, Hino O. Establishment of Tsc2‑deficient rat embryonic stem cells.INTERNATIONAL JOURNAL OF ONCOLOGY,2015
  15. Keisuke Akaike, Aiko Kurisaki-Arakawa, Kieko Hara, Yoshiyuki Suehara, Tatsuya Takagi, Keiko Mitani, Kazuo Kaneko, Takashi Yao, Tsuyoshi Saito Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential.Human pathology,46(3),347-356,2015
  16. Ishibashi T, Yaguchi A, Terada K, Ueno-Yokohata H, Tomita O, Iijima K, Kobayashi K, Okita H, Fujimura J, Ohki K, Shimizu T, Kiyokawa N.Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells.,EXPERIMENTAL HEMATOLOGY,2015
  17. Isotani S, Shimoyama H, Yokota I, China T, Hisasue SI, Ide H, Muto S, Yamaguchi R, Ukimura O, Horie S. Feasibility and accuracy of computational robot-assisted partial nephrectomy planning by virtual partial nephrectomy analysis.2015
  18. Muto S, Abe H, Noguchi T, Sugiura SI, Kitamura K, Isotani S, Ide H, Yamaguchi R, Kamai T, Horie S. Maintenance monotherapy with gemcitabine after standard platinum-based chemotherapy in patients with advanced urothelial cancer.2015
  19. Tabe Y, Konopleva M. Role of Microenvironment in Resistance to Therapy in AML.Current Hematologic Malignancy Reports,10(2),:96-103,2015
  20. Inoue M, Takahashi S, Soeda H, Shimodaira H, Watanabe M, Miura K, Sasaki I, Kato S, Ishioka C. Gene-expression profiles correlate with the efficacy of anti-EGFR therapy and chemotherapy for colorectal cancer.International Journal of Clinical Oncology,20(6),1147-55,2015
  21. Isotani S, Shimoyama H, Yokota I, Noma Y, Kitamura K, China T, Saito K, Hisasue SI, Ide H, Muto S, Yamaguchi R, Ukimura O, Gill IS, Horie S. Novel prediction model of renal function after nephrectomy from automated renal volumetry with preoperative multidetector computed tomography (MDCT). Clinical and Experimental Nephrology,2015
  22. Tomizawa D, Kato M, Takahashi H, Fujimura J, Inukai T, Fukushima T, Kiyokawa N, Koh K, Manabe A, Ohara A. Favorable outcome in non-infant children with MLL-AF4-positive acute lymphoblastic leukemia: a report from the Tokyo Children's Cancer Study Group.,INTERNATIONAL JOURNAL OF HEMATOLOGY,102,602-10,2015
  23. Keisuke Akaike, Yoshiyuki Suehara, Tatsuya Takagi, Kazuo Kaneko, Atsushi Yamashita, Takashi Yao, Tsuyoshi Saito Case Report Spindle cell lipoma of the wrist, occurring in a distinctly rare location: a case report with review of literature.International journal of clinical and experimental pathology,8(3),3299-3303,2015
  24. Midori Toda-Ishii,Keisuke Akaike,Aiko Kurisaki-Arakawa,Atsushi Arakawa,Kenta Mukaihara,Yoshiyuki Suehara,Tatsuya Takagi,Kazuo Kaneko,Takashi Yao,Tsuyoshi Saito Sarcomatous transformation of EGFR and TP53 mutation-positive metastatic adenocarcinoma of the lungs, masquerading as a primary pleomorphic sarcoma of the proximal femur.International journal of clinical and experimental pathology,8(3),3270-3278,2015
  25. Kohei Matsumoto MD, Akihito Nagahara MD, PhD, Kenshi Matsumoto MD, PhD, Yoichi Akazawa MD, Hiroyuki Komori MD, Yuta Nakagawa MD, Tsutomu Takeda MD, Hiroya Ueyama MD, PhD, Yuji Shimada MD, PhD, Daisuke Asaoka MD, PhD, Mariko Hojo MD, PhD, Sumio Watanabe MD, PhD ESTABLISHMENT OF PROPOFOL SEDATION FOR THERAPEUTIC ENDOSCOPY UNDER DEEP SEDATION WITH SPONTANEOUS RESPIRATION.Gastroenterology researh and practice,2015
  26. Masaya Kawai, Hiromitsu Komiyama, Masaki Hosoya, Haruna Okubo, Tomoaki Fujii, Norihiko Yokoyama, Chiyo Sato, Takae Ueyama, Atsushi Okuzawa, Michitoshi Goto, Yutaka Kojima, Makoto Takahashi, Kiichi Sugimoto, Shun Ishiyama, Koichiro Niwa, Yoshihiko Tashiro, Shinya Munakata, Kazuhiro Takehara, Dai Ogura, Shin-ichiro Niwa, Yuichi Tomiki, Takumi Ochiai, Kazuhiro Sakamoto Chromosome 17q deletion in the primary lesion of colorectal cancer has an impact on liver metastasis.Oncology Letters (in print)
  27. Ueno H, Hattori A, Matsunaga T, Takamochi K, Oh S, Suzuki K. Is lower zone mediastinal nodal dissection always mandatory for lung cancer in the lower lobe? SURGERY TODAY,45(11),1390-5,2015
  28. Hattori A, Suzuki K, Takamochi K, Oh S. Clinical features of multiple lung cancers based on thin-section computed tomography: What are the appropriate surgical strategies for second lung cancers?SURGERY TODAY,45(2),189-96,2015
  29. 8. Suzuki K, Watanabe S, Mizusawa J, Moriya Y, Yoshino I, Tsuboi M, Mizutani T, Nakamura K, Tada H, Asamura H; Japan Lung Cancer Surgical Study Group (JCOG LCSSG) Predictors of non-neoplastic lesions in lung tumours showing ground-glass opacity on thin-section computed tomography based on a multi-institutional prospective studydagger.Interactive Cardiovascular and Thoracic Surgery,21（2）,218-23,2015
  30. Yamada H, Tabe Y, Terao Y, Yamashita Y, Horii T, Takeda S, Ohsaka A. Clinical performance evaluation of a high-risk human papillomavirus genotyping test “Clinichip HPV” using cervical scrape specimens. Clinical Laboratory. 61(7): 851-855, 2015
  31. Matsunaga T, Suzuki K, Imashimizu K, Banno T, Takamochi K, Oh S. Body Mass Index as a Prognostic Factor in Resected Lung Cancer: Obesity or Underweight, Which Is the Risk Factor?, THORACIC AND CARDIOVASCULAR SURGEON,63(7),218-23,2015
  32. Keisuke Akaike, Midori Toda-Ishii, Yoshiyuki Suehara. Kenta Mukaihara, Daisuke Kubota, Keiko Mitani, Tatsuya Takagi, Kazuo Kaneko, Takaashi Yao, Tsuyoshi Saito. TERT promoter mutations are a rare event in gastrointestinal stromal tumors.Springer plus (in print)
  33. Kuwatsuru R, Hori S Development of intra-arterial chemoembolization for various types of cancer in humans.Juntendo Medical Journal,61(3),220-227,2015
2014年
  1. Nakagomi R, Tateishi R, Shiina S, Imamura J, Fujiwara N, Asaoka Y, Kondo K, Koike K. Drastically reduced neoplastic seeding related to radiofrequency ablation for hepatocellular carcinoma.AMERICAN JOURNAL OF GASTROENTEROLOGY,109,774-776,2014
  2. Sysa-Shah P1, Xu Y, Guo X, Bedja D, Bartock R, Tsao A, Hsieh A, Wolin MS, Moens AL, Raman V, Orita H, Gabrielson KL. Geranylgeranylacetone blocks doxorubicin-induced cardiac toxicity and reduces cancer cell growth and invasion through RHO pathway inhibition.Molecular Cancer Therapeutics,13,1717-1728,2014
  3. Tabe Y, Konopleva M. Advances in understanding the leukaemia microenvironment. BRITISH JOURNAL OF HAEMATOLOGY,164(6),767-78,2014
  4. Yoshimura M, Ishizawa J, Ruvolo V, Dilip A, Quintas-Cardama A, McDonnell TJ, Neelapu SS, Kwak LW, Shacham S, Kauffman M, McDonnell TJ, Neelapu SS, Tabe Y, Yokoo M, Kimura S, Andreeff M, Kojima K Induction of p53-mediated transcription and apoptosis by Exportin-1 (XPO1) inhibition in mantle cell lymphoma,CANCER SCIENCE,105(7),.795-801,2014
  5. Murakami A, Takahashi F, Nurwidya F, Kobayashi I, Minakata K, Hashimoto M, Nara T, Kato M, Tajima K, Shimada N, Iwakami S, Moriyama M, Moriyama H, Koizumi F, Takahashi K. Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.PLoS One.,28:9(1),e86459,2014
  6. Takei H, Morishita S, Araki M, Edahiro Y, Sunami Y, Hironaka Y, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, Komatsu N Detection of MPLW515L/K mutations and determination of allele frequencies with a single-tube PCR assay.PloS one,9(8)e104958,2014
  7. Takahashi N, Yamaguchi K, Ikenoue T, Fujii T, Furukawa Y. Identification of　two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) genePLoS One.,9(1),e86582,2014
  8. Yamaguchi K, Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M,Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y. Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.PLoS One.,9(1),e85750,2014
  9. Shiono M, Takahashi S, Kakudo Y, Takahashi M, Shimodaira H, Kato S, Ishioka C. Upper arm central venous port implantation: a 6-year single institutional retrospective analysis and pictorial essay of procedures for insertion.PLoS One,9(3),e91335,2014
  10. Iida A, Tabata Y, Baba Y, Fujii T, Watanabe S. Critical roles of DNase1l3l in lens nuclear degeneration in zebrafish. Biochimie.Biochimie,106,68-74,2014
  11. Mitsumori T, Nozaki Y, Kawashima I, Yamamoto T, Shobu Y, Nakajima K, Morishita S, Komatsu N, Kirito K Hypoxia inhibits JAK2V617F activation via suppression of SHP-2 function in myeloproliferative neoplasm cells.Experimental hematology.42(9),783-792e1,2014
  12. Soeda H, Shimodaira H, Gamoh M, Ando H, Isobe H, Suto T, Takahashi S, Kakudo Y, Amagai K, Mori T, Watanabe M, Yamaguchi T, Kato S, Ishioka C. Phase II trial of cetuximab plus irinotecan for oxaliplatin- and irinotecan-based chemotherapy-refractory patients with advanced and/or metastatic colorectal cancer: evaluation of efficacy and safety based on KRAS mutation status (T-CORE0801).Oncology,87(1),2014
  13. Aiko Kurisaki-Arakawa, Keisuke Akaike, Kieko Hara, Atsushi Arakawa, Michiko Takahashi, Keiko Mitani, Takashi Yao, Tsuyoshi Saito A case of dedifferentiated solitary fibrous tumor in the pelvis with TP53 mutation.Virchows Archiv,465(5),615-621,2014
  14. Kushida T, Nohara S, Yoshino K, Fujiwara D, Ouchi K, Amano T, Isayama F, Tomita N, Iwanuma Y, Sakai K, Tsurumaru M, Kajiyama Y. Utility of weekley docetaxel combined with preoperative radiotherapy for locally advanced esophageal cancer from pathological analysis.Diseases of the Esophagus,27,368-373,2014
  15. Tomita O, Iijima K, Ishibashi T, Osumi T, Kobayashi K, Okita H, Saito M, Mori T, Shimizu T, Kiyokawa N. Sensitivity of SNX2-ABL1 toward tyrosine kinase inhibitors distinct from that of BCR-ABL1.,LEUKEMIA RESEARCH,38,361-70,2014
  16. Ito T, Kajino K, Abe M, Sato K, Maekawa H, Sakurada M, Orita H, Wada R, Kajiyama Y, Hino O. ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.Oncology Report,31,27-33,2014
  17. Imai H, Kato S, Sakamoto Y, Kakudo Y, Shimodaira H, Ishioka C. High throughput RNAi screening identifies ID1 as a synthetic sick/lethal gene interacting with the common TP53 mutation R175H.Oncology Report.,31(3),2014
  18. Keisuke Akaike, Yoshiyuki Suehara, Tatsuya Takagi, Kazuo Kaneko, Tsuyoshi Saito An eggshell-like mineralized recurrent lesion in the popliteal region after treatment of giant cell tumor of the bone with denosumab.Skeletal radiology,43(12),1767-1772,2014
  19. Horie S, Ito S, Okada H, Kikuchi H, Narita I, Nishiyama T, Hasegawa T, Mikami H, Yamagata K, Yuno T, Muto S. Japanese guidelines of the management of hematuria 2013.Clinical and Experimental Nephrology ,18（5）,679-89,2014
  20. Kunogi H, Sakanishi T, Sueyoshi N, Sasai K Prediction of Radiosensitivity Using Phosphorylation of Histone H2AX and Apoptosis in Human Tumour Cell Lines.,INTERNATIONAL JOURNAL OF RADIATION BIOLOGY,90(7),587-593,2014
  21. Edahiro Y, Morishita S, Takahashi K, Hironaka Y, Yahata Y, Sunami Y, Shirane S, Tsutsui M, Noguchi M, Koike M, Imai K, Kirito K, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, Araki M, Komatsu N JAK2V617F mutation status and allele burden in classical Ph-negative myeloproliferative neoplasms in Japan.International journal of hematology.,99(5),625-634,2014
  22. Inoue T, Hattori T, Sugimoto S, Sasai K Design study of electron cyclotron resonance-ion plasma accelerator for heavy ion cancer therapy.,REVIEW OF SCIENTIFIC INSTRUMENTS,85(2),doi: 10.1063/1.4862208.,2014
  23. Sueyoshi R, Okawada M, Fujimura J, Saito M, Koga H, Lane GJ, Yamataka A. Successful complete resection of Ewing sarcoma arising from the bladder in a 10-year-old boy after chemotherapy.,PEDIATRIC SURGERY INTERNATIONAL,30,965-9,2014
  24. Ha YS, Kang DI, Kim JH, Joung JY, Yu J, Parihar JS, Salmasi AH, Horie S, KimWJ, Yi Kim I. Favorable risk factors in patients with positive surgical margin after robot-assisted radical prostatectomy.Canadian Journal of Urology,21（3）,Jul-90,2014
  25. Tashiro Y, Kawai M, Takehara K, Munakata S, Ishiyama S, Sugimoto K, Takahashi M, Kojima Y, Goto M, Tomiki Y, Shibuya T, Osada T, Watanabe S, Sakamoto K Successful retarieval of a retained capsule endoscope with single incision laparoscopic surgery.Case Reports in Gastroenterology,8,206-210,2014
  26. Soeda H, Shimodaira H, Watanabe M, Suzuki T, Gamo M, Takahashi M, Komine K, Kato S, Ishioka C. KRAS mutation in patients with metastatic colorectal cancer does not preclude benefit from oxaliplatin-or irinotecan-based treatment.Mol Clin Oncol.,2(3),356-362.2014
  27. Soeda H, Shimodaira H, Watanabe M, Suzuki T, Gamo M, Takahashi M, Komine K, Kato S, Ishioka C. KRAS mutation in patients with metastatic colorectal cancer does not preclude benefit from oxaliplatin-or irinotecan-based treatment.Mol Clin Oncol. ,2(3),356-362,2014
  28. Kenta Mukaihara, Daisuke Kubota, Akihiko Yoshida, Naofumi Asano, Yoshiyuki Suehara, Kazuo Kaneko, Akira Kawai and Tadashi Kondo Proteomic Profile of Epithelioid Sarcoma.Journal of Proteomics and Bioinformatics,7(6),158-165,2014
  29. Midori Toda, Yoshiyuki Suehara, Keisuke Akaike, Taketo Okubo, Daisuke Kubota, Kenta Mukaihara, Kazuo Kaneko, Takashi Yao, Tatsuya Takagi, Tsuyoshi Saito Giant-cell tumor of bone arising in the anterior rib with a positive expression of GPX-1: a case report and review of the literature.International Cancer Conference Journal,3(3),178-182,2014
  30. Kitamura K, Muto S, Yokota I, Hoshimoto K, Kaminaga T, Noguchi T, Sugiura S, Ide H, Yamaguchi R, Furui S, Horie S. Feasibility of multiparametric prostate magnetic resonance imaging in the detection of cancer distribution: histopathological correlation with prostatectomy specimens.Prostate Int,2（4）,188-95,2014
  31. Sakamoto Y, Fukaya K, Haraoka M, Kitamura K, Toyonaga Y, Tanaka M, Horie S. Analysis of prostate cancer localization toward improved diagnostic accuracy of transperineal prostate biopsy.Prostate Int.,2（3）,114-20,2014
  32. Ikeda M, Shiina S, Nakachi K, Mitsunaga S, Shimizu S, Kojima Y, Ueno H, Morizane C, Kondo S, Sakamoto Y, Asaoka Y, Tateishi R, Koike K, Arioka H, Okusaka T. Phase I study on the safety,pharmacokinetic profile,and efficacy of the combination of TSU-68, an oral antiangiogenic agent, and S-1 in patients with advanced hepatocellular carcinoma.,Invest New Drugs,32,928-936,2014
2013年
  1. Ando K, Takahashi F, Motojima S, Nakashima K, Kaneko N, Hoshi K, Takahashi K. Tocilizumab, anti-interleukin 6 receptor antibody, the new approach to cancer cachexia. JOURNAL OF CLINICAL ONCOLOGY,31（6）,e69-72,2013
  2. Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N MIP-1alpha/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia. The Journal of experimental medicine,210(12),2661-2673,2013
  3. Suzuki HI, Matsuyama H, Noguchi M, Yao T, Komatsu N, Mano H, Sugimoto K, Miyazono K Computational dissection of distinct microRNA activity signatures associated with peripheral T cell lymphoma subtypes. Leukemia,27(10),2107-2111,2013
  4. Jin L, Tabe Y, Kojima K, Shikami M, Benito J, Ruvolo V, Wang RY, McQueen T, Ciurea SO, Miida T, Andreeff M, Konopleva M PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment.JOURNAL OF MOLECULAR MEDICINE-JMM,91(12),1383-1397,2013
  5. Abe H., Mochizuki S., Ohara K., Ueno M., Ohiai H., Kitagawa Y., Hino O., Sato H. and Okada Y. Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells. AMERICAN JOURNAL OF PATHOLOGY, 183, 1667-1678,2013
  6. Jin L, Tabe Y, Lu H, Borthakur G, Miida T, Kantarjian H, Andreeff M, Konopleva M Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment. CANCER LETTERS, 329(1),45-58.,2013
  7. 20. Tabe Y, Shi YX, Zeng Z, Jin L, Shikami M, Hatanaka Y, Miida T, Hsu FJ, Andreeff M, Konopleva M TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment. PLoS One,27(8),:e62785,2013
  8. Sunami Y, Araki M, Hironaka Y, Morishita S, Kobayashi M, Liew EL, Edahiro Y, Tsutsui M, Ohsaka A, Komatsu N Inhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cells. PLoS One,8(2),e57633,2013
  9. Tateishi R, Shiina S, Akahane M, Sato J, Kondo Y, Masuzaki R, Nakagawa H, Asaoka Y, Goto T, Otomo K, Omata M, Yoshida H, Koike K. Frequency, risk factors and survaival associated with an intrasubsegmental recurrence after radiofrequency ablation for hepatocellular carcinoma.PLoS One,8,e59040,2013
  10. Tamaichi H, Sato M, Porter AC, Shimizu T, Mizutani S, Takagi M. Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.CANCER SCIENCE,104,178-82,2013
  11. Kawai A, Kobayashi T, Hino O.: Folliculin regulates cyclin D1 expression through cis-acting elements in the 3' untranslated region of cyclin D1 mRNA. INTERNATIONAL JOURNAL OF ONCOLOGY,42,1597-604,2013
  12. Fujiwara D, Kato K, Nohara S, Iwanuma Y, Kajiyama Y. The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines.Biochemical and Biophysical Research Communications ,434,773-778,2013
  13. Shirai H, Fujimori H, Gunji A, Maeda D, Hirai T, Poetsch R A, Harada H, Yoshida T, Sasai K, Okayasu R, Masutani M Parg Deficiency Confers Radio-sensitization through Enhanced Cell Death in Mouse ES Cells Exposed to Various Forms of Ionizing Radiation,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,435,100-106,2013
  14. Karasawa K, Kunogi H, Hirai T, Hoji H, Hirowatari H, Izawa H, Ito K, Sasai K, Furuya T, Ozawa S, Matsumoto F,Ito S, Oba S Radiotherapy with fraction size of 2.25 Gy in T1-2 laryngeal and hypopharyngeal cancer,JOURNAL OF RADIATION RESEARCH,54,684-689,2013
  15. Yamada H, Iijima K, Tomita O, Taguchi T, Miharu M, Kobayashi K, Okita H, Saito M, Shimizu T, Kiyokawa N. Effects of insulin-like growth factor-1 on B-cell precursor acute lymphoblastic leukemia.,INTERNATIONAL JOURNAL OF HEMATOLOGY,97,73-82,2013
  16. Furuya T, Sugimoto S, Kurokawa C, Ozawa S, Karasawa K, Sasai K The dosimetric impact of respiratory breast movement and daily setup error on tangential whole breast irradiation using conventional wedge, field-in-field and irregular surface compensator techniques.,JOURNAL OF RADIATION RESEARCH,54(1),157-165,2013
  17. Nagayasu K, Komiyama H, Ishiyama S, Ogura D, Takahashi R, Tashiro Y, Niwa K, Sugimoto K, Kojima Y, Goto M, Tomiki Y, Niwa S, Sakamoto K Investigation of free cancer cells in peripheral blood using CEA mRNA expression in perioperative colorectal cancer patients.Molecular and clinical oncology,1,668-674,2013
  18. Sugimoto K, Kawai M, Takehara K, Tashiro Y, Munakata S, Ishiyama S, Komiyama H T1 colorectal cancer with synchronous linver metastasis.Case Reports in Gastroenterology,43,1031-1038,2013
  19. Nagayasu K, Komiyama H, Ishiyama S, Ogura D, Takahashi R, Tashiro Y, Niwa K, Sugimoto K, Kojima Y, Goto M, Tomiki Y, Niwa S and Sakamoto K. Investigation of peripheral blood free cancer cells using CEA mRNA expression in perioperative colorectal cancer patients.Molecular and Clinical Oncology,1（4）,668-674,2013
  20. Kawashima M, Ozawa S, Haga A, Sakumi A, Kurokawa C, Sugimoto S, Karasawa K, Nakagawa K, Sasai K. Comparison of total MU and segment areas in VMAT and step-and-shoot IMRT plans.,Radiol Phys Technol.,6(1),14-20,2013
  21. Usui K, Ichimaru Y, Okumura Y,Murakami K, Seo M, Kunieda E, Ogawa K, Dose calculation with a cone beam CT image in image-guided radiation therapy.,Radiol Phys Tech,6,107-114,2013
2012年
  1. Tashiro Y, Nishida C, Sato-Kusubata K, Ohki-Koizumi M, Ishihara M, Sato A, Gritli I, Komiyama H, Sato Y, Dan T, Miyata T, Okumura K, Tomiki Y, Sakamoto K, Nakauchi H, Heissig B, Hattori K. Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice.Blood,119,6382-6393,2012
  2. Tabe Y, Jin L, Iwabuchi K, Wang R, Ichikawa N, Miida T, Cortes J, Andreeff M, Konopleva M Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts. Leukemia,26(5),883-92,2012
  3. Kanemitsu N, Isobe Y, Masuda A, Momose S, Higashi M, Tamaru J, Sugimoto K, Komatsu N Expression of Epstein-Barr virus-encoded proteins in extranodal NK/T-cell Lymphoma, nasal type (ENKL): differences in biologic and clinical behaviors of LMP1-positive and -negative ENKL.CLINICAL CANCER RESEARCH,18(8),2164-2172,2012
  4. Shiina S, Tateishi R, Arano T, Uchino K, Enooku K, Nakagawa H, Asaoka Y, Sato T, Masuzaki R, Kondo Y, Goto T, Yoshida H, Omata M, Koike K. Radiofrequency ablation for hepatocellular carcinoma 10-year outcome and prognostic factors.AMERICAN JOURNAL OF GASTROENTEROLOGY,107,569-577,2012
  5. Yae S, Takahashi F, Yae T, Yamaguchi T, Tsukada R, Koike K, Minakata K, Murakami A, Nurwidya F, Kato M, Tamada M, Yoshikawa M, Kobayashi H, Seyama K, Takahashi K. Hochuekkito (TJ-41), a Kampo formula, ameliorates cachexia induced by colon 26 adenocarcinoma in mice. Evidence-Based Complementary and Alternative Medicine, 2012, 976926, 2012, DOI:10.1155/2012/976926
  6. Shiina S, Tateishi R, Imamura M, Teratani T, Koike Y, Sato S, Obi S, Kanai F, KatoN, Yoshida H, Omata M, Koike K. Percutaneous ethanol injection for hepatocellular carcinoma 20-year outocome and prognostic factors.LIVER INTERNATIONAL,32,1434-1442,2012
  7. Hirai T, Shirai H, Fujimori H, Okayasu R, Sasai K, Masutani M　 Radiosensitization Effect of PARP Inhibitor in Cells Exposed to Low and High LET Radiation.,Cancer Science,103（6）,1045-1050,2012
  8. Minakata K, Takahashi F, Nara T, Hashimoto M, Tajima K, Murakami A, Nurwidya F, Yae S, Koizumi F, Moriyama H, Seyama K, Nishio K, Takahashi K. Hypoxia induces gefitinib resistance in non-small cell lung cancer with both mutant and wild-type epidermal growth factor receptors.Cancer Science,103(11)、1946-54、2012
  9. Karasawa K, Matsumoto F, Ito S, Oba S, Furuya T, Hirowatari H, Izawa H, Ito K, Sasai K. Hyperfractionated radiotherapy with concurrent docetaxel for advanced head and neck cancer: a phase II study.,ANTICANCER RESEARCH,39（2）,4013-4018,2012
  10. Hojo H, Zenda S, Akimoto T, Kohno R, Kawashima M, Arahira S, Nishio T, Tahara M, Hayashi R, Sasai K. Impact of early radiological response evaluation on radiotherapeutic outcomes in the patients with nasal cavity and paranasal sinus malignancies., JOURNAL OF RADIATION RESEARCH,53(5),704-709,2012
  11. Kawase E, Karasawa K, Shimotsu S, Izawa H, Hirowatari H, Saito AI, Ito K, Horikawa N. Estimation of anxiety and depression in patients with early stage breast cancer before and after radiation therapy.,Breast Cancer,19（2）,147-152,2012
  12. arasawa K, Kunogi H, Hirai T, Hojo H, Hirowatari H, Izawa H, Ito K, Sasai K, Kawashima M, Furuya T, Sugimoto S, Kurokawa C, Ozawa S, Saito M. Comparison of hypofractionated and conventionally fractionated whole-breast irradiation for early breast cancer patients: a single-institute study of 1,098 patients.,Breast Cancer. 2012 ,21(4),402-408,2014
  13. Motomi Nasu, Michael K.Gibson, Malcolm Brock, Hajime Orita, Li Xu, James Herman, Arlene Forastiere, Yoshiaki Kajiyama, Masahiko Tsurumaru Field Defect of Methylation Changes in Esophageal Adenocarcinomas in Patients from Japan and the United States. Cancer Therapy,8,105-108,2012
  14. Minowa K, Suzuki M, Fujimura J, Saito M, Koh K, Kikuchi A, Hanada R, Shimizu T. L-asparaginase-induced pancreatic injury is associated with an imbalance in plasma amino acid levels.,Drugs R D.,12,49-55,2012
2011年
  1. Kunii R, Jiang S, Hasegawa G, Yamamoto T, Umezu H, Watanabe T, Tsuchida M, Hashimoto T, Hamakubo T, Kodama T, Sasai K, Naito M.　 The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid　transcription factor-1 (TTF-1)-negative pulmonary adenocarcinoma,Histopathology,58(3),467-476,2011
  2. Ariizumi S, Kitagawa K, Kotera Y, Takahashi Y, Katagiri S, Kuwatsuru R, Yamamoto M A non-smooth tumor margin in the hepatobiliary phase of gadoxetic acid disodium (Gd-EOB-DTPA)-enhanced magnetic resonance imaging predicts microscopic portal vein invasion, intrahepatic metastasis, and early recurrence after hepatectomy in patients with hepatocellular carcinoma.Journal of Hepato-Biliary-Pancreatic Sciences,18(4),575-85,2011
  3. Izawa H, Hirowatari H, Yahata Y, Hamano Y, Ito K, Saito AI, Yamamoto H, Miura K, Karasawa K, Sasai K. Effect of dose fractionation on pulmonary complications during total body irradiation. , JOURNAL OF RADIATION RESEARCH,52,502-508,2011
  4. Suzuki H, Kondo T, Kuwatsuru R, Wada K, Kubota M, Kobayashi H, Iizuka J, Ikezawa E, Takagi T, Tanabe K Decompressive surgery in combination with preoperative transcatheter arterial embolization: Successful improvement of ambulatory function in renal cell carcinoma patients with metastatic extradural spinal cord compression.INTERNATIONAL JOURNAL OF UROLOGY,18(10),718-22,2011
  5. Inage E, Saito M, Saito Y, Takata O, Fujimura J, Yamataka A, Shimizu T. Contralateral pleural recurrence of adrenocortical carcinoma after surgical resection.,Pediatr Int.,53,600-603,2011
2010年
  1. Ichikawa T, Saitou K, Yoshioka N, Tanimoto A, Gokan T, Takehara Y, Kamura T, Gabata T, Murakami T, Ito K, Horihashi S, Nishie A, Saito Y, Onaya H, Kuwatsuru R, Morimoto A, Ueda K, Kurauchi M, Breuer J Detection and characterization of focal liver lesions: a Japanese phase III, multicenter comparison between gadoxetic acid disodium-enhanced magnetic resonance imaging and contrast-enhanced computed tomography predominantly in patients with hepatocellular carcinoma and chronic liver disease.INVESTIGATIVE RADIOLOGY,45(3),133-141,2010
  2. Tan K., Kajino K., Momose S., Masaoka A., Sasahara K., Shiomi K., Izumi H., Abe M., Ohtsuji N., Wang T., Hino O. and Fujii H.: Mesothelin (MSLN) promoter is hypomethylated in malignant mesothelioma, but its expression is not associated with methylation status of the promoter. HUMAN PATHOLOGY,41, 1330-1338,2010
  3. Fujimura J, Takeda K, Kaduka Y, Saito M, Akiba H, Yamashiro Y, Shimizu T, Okumura K. Contribution of B7RP-1/ICOS co-stimulation to lethal acute GVHD.,Pediatr Transplantation,14,540-8,2010
  4. Orita H, Coulter J, Tully E, Abe M, Montgomery E, Alvarez H, Sato K, Hino O, Kajiyama Y, Tsurumaru M, Gabrielson E. High levels of fatty acid synthase expression in esophageal cancers represent a potential target for therapy.Cancer Biology & Therapy,10,549-554,2010
  5. Sakai N, Kajiyama Y, Iwanuma Y, Tomita N, Amano T, Isayama F, Ouchi K, Tsurumaru M. Study of abnormal chromosome regions in esophageal squamous cell carcinoma by comparative genomic hybridization: relationship of lymph node metastasis and distant metastasis to selected abnormal regions.Diseases of the Esophagus,23,415-421,2010
  6. Kawaguchi G, Abe E, Sasamoto R, Sasai K. Elevation of serum carcinoembryonic antigen level in a patient with hypothyroidism after radiation therapy for cervical esophageal cancer., Int J Clin Oncol. ,15(1),104-108,2010
2009年以前
  1. Toshio Takayama , Masahiko Tsurumaru, Yoshiaki Kajiyama, Yoshimi Iwanuma, Natsumi Tomita, Takayuki Amano, Fuyumi Isayama, Tomoaki Ito Setting of the candidate exposure conditions in an individualized tumor response testing (ITRT) toward an individual chemotherapy for esophageal cancer.Esophagus,5,87-91,2008

学会発表

2015年
  1. Sekihara K, Noda A. Hypertonic treatment increases radiation-induced unrepairable DNA damages in cultured human cells,15th International Congress of Radiation Research,Kyoto
  2. Sekihara K, Yamamoto S, Kikkawa M, Taka H, Kaga Y, Matsushita H, Hayashi H, Tanaka M, Miida T, Andreeff M, Konopleva M, Tabe Y. mTOR kinase inhibitor AZD-2014 enhances the antitumor effects of XPO1 antagonist KPT-185 in mantle cell lymphoma,European Society for Medical Oncology (ESMO) Asia 2015 Congress,Singapore
  3. Shinichi Yamamoto, Yoko Tabe Novel FAO inhibitor avocatin B induces apoptosis of acute monocytic leukemia cells in adipocyte co-culture system via ER stress and ATF4 activation.,57th American Society of Hematology (ASH) Annual Meeting and Exposition,Orlando
  4. Yoko Tabe, Marina Konopleva, Norikazu Monma, Kazuho Ikeo, Kaoru Mogushi, Yasunari Yamanaka, Hiromichi Matsushita, Takashi Miida, Yoshihide Hayashizaki, Michael Andreeff Cap analysis of gene expression (CAGE) sequencing reveals alterations of the transcript signatures in acute monocytic leukemia cells by fatty acid oxidation inhibition,57th American Society of Hematology (ASH) Annual Meeting and Exposition,Orlando
  5. Jo Ishizawa, Rodrigo Omar Jacamo, Kensuke Kojima, Dhruv Chachad, Vivian Ruvolo, Peter Ruvolo, Weiguo Zang, Yoko Tabe, Marina Konopleva, William Devine, Susan Lindquist, John A Porco, Luke Whitesell, Michael Andreeff Inactivating Heat Shock Factor 1 (HSF1) in Acute Myeloid Leukemia By Pharmacological Inhibition of eIF4a: A Promising Therapeutic Approach ,57th American Society of Hematology (ASH) Annual Meeting and Exposition,Orlando
  6. Jo Ishizawa, Kensuke Kojima, Dhruv Chachad, Peter Ruvolo, Vivian Ruvolo, Rodrigo Omar Jacamo, Gautam Borthakur, Hong Mu, Zhihong Zeng, Yoko Tabe, Joshua Allen, Zhiqiang Wang, Wencai Ma, Hans Lee, Robert Z. Orlowski, Dos D. Sarbassov, Sattva S. Neelapu, Timothy J. McDonnell, Roberto N. Miranda, Michael Wang, Hagop M Kantarjian, Marina Konopleva, Richard Eric Davis, Michael Andreeff ONC201 Induces p53-Independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies By Induction of ATF4 through Integrated Stress Response ,57th American Society of Hematology (ASH) Annual Meeting and Exposition,Orlando
  7. Ce Shi, Lina Han, Qi Zhang, Kathryn G. Roberts, Eugene Park, Yoko Tabe, Rodrigo Omar Jacamo, Hong Mu, Shuo-Chieh Wu, Jin Zhou, Helen Ma1, Zhihong Zeng, Nitin Jain, Elias J Jabbour, Markus Muschen1, Sarah K Tasian, Charles G. Mullighan, David M. Weinstock, David Fruman, Marina Konop Combined Targeting of JAK2 with a Type II JAK2 Inhibitor and mTOR with a TOR Kinase Inhibitor Constitutes Synthetic Activity in JAK2-Driven Ph-like Acute Lymphoblastic Leukemia ,57th American Society of Hematology (ASH) Annual Meeting and Exposition,Orlando
  8. Kato M, Shukuya T, Kanemaru R, Honma Y, Muraki K, Shibayama R, Koyama R, Shimada N, Takahashi F, Takahashi K. Cerebral infarction in advanced non-small cell lung cancer,Congress of Asian Pacific Society of Respirology (APSR) 2015,Kuala Lumpur
  9. Yagishita S, Fujita Y, Fujimoto Y, Takahashi F, Takahashi K, Tamura T, Koizumi F. Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer,Congress of American Association for Cancer Research (AACR) 2015,Philadelphia
  10. Edahiro Y, Araki M, Hironaka Y, Yang Y, Morishita S, Sunami Y, Ohsaka A, Komatsu N. Activation of AP-1 By JAK2V617F through Induction and Stabilization of c-FOS,57th Annual Meeting of the American Society of Hematology,Orlando
  11. Takuya Ueda, T. Matsunaga, S. Oh, K. Takamochi, K. Suzuki POSTOPERATIVE ATRIAL FIBRILLATION IS LESS FREQUENT IN SEGMENTECTOMY COMPARED WITH PULMONARY LOBECTOMY,ESTS – 23rd　European Society of Thoracic Surgeons,Lisbon IPA
  12. Suehara Y, Kohsaka S, Mukaihara K, Akaike K, Ishii M, Kubota D, Kazuno S, Mineki R, Fujimura T, Kaneko K, Ladanyi M, Saito T. Proteomic approaches for defining the protein profiles of EWS/FLi1 in Ewing's sarcomas.,ORS 2015 Annual Meeting,Nevada
  13. Keisuke Akaike, Aiko Kurisaki-Arakawa, Kieko Hara, Yoshiyuki Suehara, Tatsuya Takagi, Kazuo Kaneko, Takashi Yao, Tsuyoshi Saito Distinct Clinicopathologic Features Of Nab2-stat6 Fusion Gene Variants In Solitary Fibrous Tumor With Emphasis On The Acquisition Of Highly Malignant Potential. ,ORS 2015 Annual Meeting,Nevada,2015/3
  14. Midori Ishii, Yoshiyuki Suehara, Keisuke Akaike, Kenta Mukaihara, Daisuke Kubota, Taketo Okubo, Tatsuya Takagi, Takashi Yao, Kazuo Kaneko, Tsuyoshi Saito Clinicopathological impact of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors.,2015 ASCO Annual Meeting,Chicago
  15. Tatsuya Takagi, Hirohisa Katagiri, Yongji Kim, Yoshiyuki Suehara, Daisuke Kubota, Keisuke Akaike, Midori Ishii, Kenta Mukaihara, Taketo Okubo, Yasuo Yazawa, Mitsuru Takahashi, Kazuo Kaneko, Tsuyoshi Saito Skeletal metastasis of unknown primary origin at the initial visit: A retrospective analysis of 286 cases,ISOLS-MSTS Combined Meeting,Orland
  16. Kenta Mukaihara, Daisuke Kubota, Yoshiyuki Suehara, Keisuke Akaike, Midori, Ishii, Tatsuya Takagi, Shinji Kohsaka, Kazuo Kaneko, Tsuyoshi Saito Protein expression profiling of giant cell tumors of bone treated with denosumab,ISOLS-MSTS Combined Meeting,Orland
  17. Keisuke Akaike, Yoshiyuki Suehara, Kenta Mukaihara, Aiko Kurisaki-Arakawa, Daisuke Kubota, Taketo Okubo, Midori, Ishii, Hiroyuki Mitomi, Michiko Takahashi, Tatsuya Takagi, Kazuo Kaneko, Takashi Yao, Tsuyoshi Saito KCTD12 may be negatively regulated by KIT in gastrointestinal stromal tumors ,2015 CTOS Annual Meeting,Salt Lake City
  18. Midori Ishii, Yoshiyuki Suehara, Keisuke Akaike, Kenta Mukaihara, Daisuke Kubota, Taketo Okubo, Tatsuya Takagi, Takashi Yao, Kazuo Kaneko, Tsuyoshi Saito Clinicopathological impact of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors,2015 CTOS Annual Meeting,Salt Lake City
  19. Midori Ishii, Yoshiyuki Suehara, Keisuke Akaike, Kenta Mukaihara, Daisuke Kubota, Taketo Okubo, Tatsuya Takagi, Takashi Yao, Kazuo Kaneko, Tsuyoshi Saito Clinicopathological and functional analyses of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors,ESMO-ASIA 2015,Singapor
  20. Kohei. Matsumoto, H. Ueyama, Kenshi. Matsumoto, Y. Akazawa, H. Komori, T. Takeda, T. Murakami, A. Nagahara, T. Yao, S. Watanabe CLINICOPATHOLOGICAL FEATURES OF ALPHA-FETOPROTEIN -PRODUCING GASTRIC CANCER WITH ENTEROBLASTIC DIFFERENTIATION,UEGW 2015,Barcelona
  21. S.Yoshikawa, M.Fukuaga, K.Nagakari, Y.Lee, M.Sugano, M.Suda, Y.Iida, Y.Ito, M.Ouchi, G.Katsuno, Y.Hirasaki, M. Ito, D.Azuma, S. Kohama, J. Nomoto, A. Mizushima, Evaluation of the laparoscopic palliative operations for malignant bowel obstruction,21st. World Congress of the EAES ,Bucharest, Romania
  22. Hiroyuki Tamaichi, Sachi Sakaguchi, Junya Fujimura, Akihide Kondo, Jun Ando, Tatsuya Takagi, Tomoko Kurimoto, Hiroyuki Yamada, Yohei Saito, Masahiro Saito Toshiaki Shimizu The management of Adolescents and Young Adults with cancers,9th St. Jude Viva Forum in Pediatric Oncology,Singapole
  23. Shiina S. WHICH ABLATION. Ablation of HCC: The Eastern perspective.,Ewalt (Eastern & Western Association Liver Tumors),Milan
  24. Shiina S. Hepatocellular carcinoma: current management and recent advances.,Seminario in Campus Bio Medico University of Rome,Rome
  25. Shiina S. Hepatocellular carcinoma: management update: What is the ideal therapy for HCC? Ablation,APASL 2015,Istanbul
2014年
  1. Tabe Y, Harada M, Miyamae Y, Matsushita H, Kojima K, Fujimura T, Kazuno S, Ueno T, Miida T, Konopleva M, Andreeff M: The mTOR kinase inhibitor AZD-2014 effectively reverses XPO1/CRM1 antagonist KPT-185–induced glycolysis / gluconeogenesis, enhancing antitumor effects in mantle cell lymphoma. ,56th American Society of Hematology (ASH) Annual Meeting and Exposition,San Francisco
  2. Tabe Y, Harada M, Miyamae Y, Fujimura T, Kazuno S, Ueno T, Miida T, Andreeff M, Konopleva M: Metabolic re-programming in Notch-activated T-ALL by mTOR inhibitor AZD2014 combined with L-Asparaginase. ,56th American Society of Hematology (ASH) Annual Meeting and Exposition,San Francisco
  3. Tabe Y, Harada M, Miyamae Y, Mogushi K, Kazuno S, Fujimura T, Matsushita T, Ueno T, Yokomizo T, Miida T, Samudio I, Andreeff M, Konopleva M: Bone marrow adipocyte-derived free fatty acids induce gene signature linking transcription with metabolic changes that contribute to survival of acute monocytic leukemia cells. ,56th American Society of Hematology (ASH) Annual Meeting and Exposition,San Francisco
  4. Nurwidya F, Takahashi F, Murakami A, Kobayashi I, Kato M, Minakata K, Yagishita S, Koyama R, Muraki K, Takahashi M, Shimada N, Takahashi K. Epithelial-mesenchymal transition-driven gefitinib resistance in non-small cell lung cancer is mediated by zinc-finger E-box protein 1.,Congress of American Thoracic Society (ATS) 2014,San Diego
  5. Kobayashi I, Takahashi F, Nurwidya F, Murakami A, Kato M, Shimada N, Suina K, Kanemaru R, Yagishita S, Ko R, Asao T, Ohashi R, Muraki K, Yoshioka Y, Takahashi M, Takahashi K. Oct4 plays a key role in the persistence of gefitinib-resistant lung cancer stem cells. ,Congress of the Asian Pacific Society of Respirology (APSR) 2014,Kota Denpasar
  6. Nurwidya F, Takahashi F, Kobayashi I, Shimada N, Murakami A, Baskoro H, Suina K, Kanemaru R, Yagishita S, Asao T, Ohashi R, Muraki K, Yoshioka Y, Takahashi M, Sasaki S, Takahashi K. Translational Evidence of Zinc finger E-box binding homeoprotein 1 Involvement in Acquired Resistance to Gefitinib in Non-small Cell Lung Cancer,Congress of the Asian Pacific Society of Respirology (APSR) 2014,Kota Denpasar
  7. Sunami Y, Araki M, Ito A, Hironaka Y, Ohsaka A, Yoshida M, Komatsu N Histone acetyltransferase PCAF is required for ATRA-induced granulocytic differentiation in APL cells. ,35th World Congress of the International Society of Hematology,Beijing
  8. Harada H, Harada Y, Inoue D, Sashida G, Iwama A, Nakajima H, Komatsu N, Kitamura T C-terminal truncation type of RUNX1 mutants induce MDS/AML via gain-of-function mechanisms.,ISEH 43rd Annual Scientific Meeting,Montreal
  9. Sunami Y, Araki M, Ito A, Hironaka Y, Ohsaka A, Yoshida M, Komatsu N Histone acetyltransferase PCAF is required for ATRA-induced granulocytic differentiation in acute promyelocytic leukemia cells.,56th Annual Meeting of the American Society of Hematology,San Francisco
  10. Shirane S, Araki M, Morishita S, Hironaka Y, Noguchi M, Koike M, Hirano T, Ohsaka A, Komatsu N Dynamic Increase in JAK2V617F Allele Burden Is a Predictive Parameter for the Transformation into Myelofibrosis from Polycythemia Vera and Essential Thrombocytosis.,56th Annual Meeting of the American Society of Hematology,San Francisco
  11. Ishibashi M, Tamura H, Sunakawa M, Kondo-Onodera A, Moriya K, Okuyama N, Hamada Y, Isoda A, Matsumoto M, Sasaki M, Komatsu N, Handa H, Imai Y, Tanaka J, Tanosaki S, Ito S, Ishida Y, Koike M,  Tamada K, Inokuchi K. Interaction Between B7-H1 Molecules on Myeloma Cells and PD-1 Molecules on T Cells Induces Resistance to Antimyeloma Chemotherapy.,56th Annual Meeting of the American Society of Hematology,San Francisco
  12. Yamada A, Tamura H, Ishibashi M, Inokuchi K, Sasaki M, Yahata Y, Komatsu N, Isoda A, Matsumoto M, Handa H;  Imai Y, Tanaka J, Tanosaki S,  Ito S, Ishida Y, Koike M Clinical Utility of Slam Family Member CD229 in Identifying Tumor Cells and High-Risk Disease Markers, CD86 (B7-2) and CD126 (IL-6 receptor), Using Flow Cytometric Analysis in Multiple Myeloma.,56th Annual Meeting of the American Society of Hematology,San Francisco
  13. Kazuhiro Sakamoto, Ro Hisashi, Kure Kazumasa, Honjo Kumpei, Aoki Jun, Okazawa Yu, Takehara Takahashi Rina, Ishiyama Shun, Sugimoto Kiichi, Yaginuma Hiroyuki, Takahashi Makoto, Kojima Yutaka, Goto Michitoshi, Okuzawa Atsushi, Tomiki Yuichi LAPAROSCOPIC ABDOMINOPERINEAL RESECTION FOR RECTAL CANCER,The 14th World Congress of Endoscopic Surgery,Paris
  14. Shingo Ito，Kazuhiro Sakamoto，Yuichi Tomiki，Atsushi Okuzawa，Michitoshi Goto，Yutaka Kojima，Hiromitsu Komiyama，Makoto Takahashi，Yukihiro Yaginuma，Shun Ishiyama，Kiichi Sugimoto，Masaya Kawai，Kazuhiro Takehara，Yoshihiro Tashiro，Shinya Munakata，Hisashi Ro，Kosuke Mizukoshi，Jun Aoki，Yuu Okazawa，Rina Takahashi，Kumpei Honjo，Ryousuke Ichikawa，Kazumasa Kure EXPERIENCE OF SINGLE-INCISION LAPAROSCOPIC SURGERY FOR THE SMALL INTESTINE LESION，The Society of American Gastrointestinal and Endoscopic Surgeons,Salt Lake City
  15. Sugimoto K, Sakamoto K, Tomiki Y, Goto M, Kojima Y, Komiyama H, Takahashi M, Ishiyama S, Ito S, Kawai M, Takehara K, Tashiro Y, Munakata S, Aoki J, Okazawa Y, Takahashi R and Mizukoshi K Long-term outcome in laparoscopic colectomy for colon cancer,The Society of American Gastrointestinal and Endoscopic Surgeons,Salt Lake City
  16. Kenta Mukaihara, Daisuke Kubota, Yoshiyuki Suehara, Keisuke Akaike, Midori, Ishii, Tatsuya Takagi, Shinji Kohsaka, Kazuo Kaneko, Tsuyoshi Saito Functional analysis of F-actin-capping protein subunit beta in epithelioid sarcomas ,2014 CTOS Annual Meeting,Berlin
  17. Kenta Mukaihara, Daisuke Kubota, Yoshiyuki Suehara, Keisuke Akaike, Midori, Ishii, Tatsuya Takagi, Shinji Kohsaka, Kazuo Kaneko, Tsuyoshi Saito Protein expression profiling of giant cell tumors of bone treated with denosumab ,2014 CTOS Annual Meeting,Berlin
  18. Kurokawa C, Urushiyama A, Nishio T Characteristics of tissue-equivalent thermoluminescence and photo-stimulated luminescence sheets,ESTRO　33, Austria (Vienna)
  19. Sugimoto S, Utsunomiya S, Ebe K, Inoue T, Kurokawa C, Usui K, Sasai K Dose Calculation Method for Dynamic Tumor Tracking Using a Gimbal-Mounted Linac,56th AAPM Annual Meeting and Exhibition,Austin
  20. Nagata H, Sugimoto S, Hongo H, Hashimot H, Kurokawa C, Usui K, Inoue T, Kawabata T, Omura M, Sasai K Investigation for characteristic and quality control of megavoltage computed tomography image noise on helical tomotherapy unit,The 14th Asia-Oceania Congress of Medical Physics &The 12th South East Asia Congress of Medical Physics,Ho Chi Minh city
  21. Tomoko Kurimoto, Akihide Kondo , Ikuko Ogino , Sachi Sakaguchi, Junya Fujimura, Masahiro Saito, Atsushi Arakawa, Hajime Arai, Toshiaki Shimizu Correlation of clinical outcome with expression of O6-methylguanine-DNA methyltransferase (MGMT) in patients with medulloblastoma.,16th International Symposium on Pediatric Neuro-Oncology,Singapole
  22. Fujimura Junya, Saito Youhei, Sakaguchi Sachi, Saito Masahiro, Shimizu Toshiaki Acute myeloid leukemia-type chemotherapy for early T-cell precursor acute lymphoblastic leukemia: A case report ,8th St. Jude Viva Forum in Pediatric Oncology,Singapole
  23. Sakaguchi S, Higa T, Suzuki M, Fujimura J, Shimizu T Prophylactic use of octreotide for asparaginase-induced acute pancreatitis,46th Congress of the International Society of Paediatric Oncology,Tronto
2013年
  1. Murakami A, Takahashi F, Nurwidya F, Kobayashi I, Minakata K, Kato M, Ohashi R, Shimada N, Takahashi K. Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.,Congress of the Asian Pacific Society of Respirology (APSR) 2013,Yokohama
  2. Ando K, Takahashi F, Kato M, Kaneko N, Yae S, Yae T, Hoshika Y, Doi T, Takahashi K. Possible role of Tocilizumab for cachectic patients with interleukin-6 expressing lung cancer.,Congress of the Asian Pacific Society of Respirology (APSR) 2013,Yokohama
  3. Nurwidya F, Takahashi F, Murakami A, Kobayashi I, Kato M, Shukuya T, Ko R, Yagishita S, Koyama R, Muraki K, Takahashi M, Shimada N, Takahashi K. Knockdown of zinc-finger E-box-binding homeobox 1 (ZEB1) reduces stem cells characteristic of gefitinib-resistant-persisters of PC9 cells.,Congress of the Asian Pacific Society of Respirology (APSR) 2013,Yokohama
  4. Kobayashi M, Araki M, Hironaka Y, Ohsaka S, Komatsu N Identification of FOXO3A as a key downstream target for the oncogenic JAK2V617F,55th Annual Meeting of the American Society of Hematology,New Orleans
  5. Sakamoto K, Okazawa Y, Kawai M, Takehara K, Tashiro Y, Niwa K, Nagayasu K, Ishiyama S, Sugimoto K, Takahashi M, Kojima Y, Goto M, Tomiki Y Laparoscopic intersphincteric resection using needlescopic instruments,ＳＡＧＥＳ,Baltimore
  6. Takuya Ueda, Kenji Suzuki, Mariko Fukui, Takeshi Matsunaga, Shiaki Oh, Kazuya Takamochi Pneumonectomy, Bronchoplasty, Pulmonary Arterioplasty, and Combined Resections of the Superior Vena Cava are Feasible even in Salvage Surgery following Definitive Chemoradiotherapy (60-66Gy) for Lung Cancer;The 15th World Conference on Lung Cancer, Sydney
  7. Kurokawa C, Urushiyama A, Nishio T, Sugimoto S Characteristics of TLD and PSLD Films for Photon and Electron Dose Measurements,55th AAPM Annual Meeting,,Indianapolis
  8. Inoue T, Hattori T, Sugimto S, Sasai K Evaluation of inherent dose uncertainty for VMAT using dose-uncertainty model,55th AAPM Annual Meeting,Indianapolis
  9. Usui K, Kunieda E, Ogawa K The effect of region extraction accuracy on the dose calculation with CBCT images combined with MSCT images.,Annual Meeting on European Congress of Radiology,Vienna
  10. Usui K, Kunieda E, Ogawa K The study of the 4D CBCT reconstruction using the detection of the target position from the 2D projection images.,55th ASTRO Annual Meeting, Atlanta
  11. A I Saito,T Asahina,Y Kosugi,M Nakashiro,H Hojo,T Hirai,H Kunogi,K Ito,S Ishikura,K Sasai Bra cup size a reliable confounding factor for the evaluation of acute skin toxicity caused by radiation therapy in breast therapy?,ASTRO the2013 Annual Meeting,Atranta
  12. Shiina S. HCC-Asian perspective and management.,The 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL),Singapore
2012年
  1. Kato M, Takahashi F, Koyama R, Muraki K, Kanemaru R, Ko R, Kobayashi I, Murakami A, Hoshika Y, Shyukuya T, Ohashi R, Shimada N, Sakuraba A, Takahashi K. Efficacy and safety of Pemetrexed for non-small cell lung cancer patients with idiopathic interstitial pneumonia.,Congress of the Asian Pacific Society of Respirology (APSR) 2012, Hong Kong
  2. Sunami Y, Araki M， Morishita S， Hironaka Y, Edahiro Y, Ohsaka A，Komatsu N The Sirtuin inhibitor induces APL cell differentiation,The 3rd JSH International Symposium 2012,Kawagoe
  3. Kunogi H, Sasai K. Prediction of radiosensitivity using phosphorylation of Histone H2AX.,The International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe,Geneva Switzerland
  4. Kunogi H, Hojo H, Nakashiro M, Hirai T, Saito AI, Ito K, Wakumoto Y Sasai K Postimplant Prostate CT-MRI Fusion Technique Using Fat-Suppressed T1-Weighted Images, World Congress of Brachytherapy,Barcelona, Spain
  5. Sugimoto S, Ozawa S, Takatou H, Tokuyama K, Maruyama H, Yamagishi T, Baba R, Ebe K, Sasai K Study of Restricted Mass Stopping Power Ratio in Small Electron Tube Fields,2012 AAPM Annual Meeting,Charlotte, North Carolina
  6. Inoue T, Sugimoto S, Fukata K, Kurokawa C, Ozawa S, Sasai K Evaluation of the Energy Dependence of Gafchromic EBT3 Film for Electron Beams,2012 AAPM Annual Meeting,Charlotte, North Carolina
  7. Junya Fujimura, Sachi Sakaguchi, Akihide Kondo, Youhei Saito, Kazuaki Shimoji, Yuko Ohara, Atsushi Arakawa, Masahiro Saito, Toshiaki Shimizu Congenital non-specified sarcoma with neuronal differentiation of the left orbit,14th International Symposium on Pediatric Neuro-Oncology,Tronto
  8. Shiina S. Multidisciplinary approach in colorectal cancer conference radiofrequency ablation (RFA) for CRLM: a 10-year experience,Taiwan Society of Coloproctology,Taipei
2011年
  1. Orita H, Abe M, Sato K, Hina O, Kajiyama Y, Tsurumaru M, Gabrielson E Serum fatty acid synthase as a marker of esophageal neoplasia.,1st The Inaugural International Academy of Sportology,Tokyo
  2. Circulating micrometastases of esophageal cancer detected by carcinoembryonic antigen mRNA reverse transcriptase-polymerase chain reaction: clinical implications,8th International Symposium on Minimal Residual Cancer,Osaka
2010年
  1. Minakata K, Takahashi F, Murakami A, Tajima K, Nurwidya F, Yae S, Yae T, Muraki K, Shukuya T, Koyama R, Ohashi R, Mori T, Seyama K, Takahashi K. Genetic Heterogeneity of Epidermal Growth Factor Receptor and Hypoxia are Important Factors in Resistance to Gefitinib in Non-Small Cell Lung Cancer. ,Congress of the Asian Pacific Society of Respirology (APSR) 2010,Manila
  2. Orita H, Coulter J, Tully E, Abe M, Montgomery E, Alvarez H, Sato K, Hino O, Kajiyama Y, Tsurumaru M, Gabrielson E. High levels of fatty acid synthase expression in esophageal cancers represent a potential target for therapy,AACR 101st Annual Meeting 2010 ,Washington D C